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Agent-based Literature Curation

What is this?

Validation of AI Agent-Based Curation for Low-Noise Literature Set Construction

This repository provides complete research materials for validating AI agent-based literature curation methods, including:

  • Comprehensive research documentation and findings
  • Full analysis scripts and implementation code
  • Experimental datasets and evaluation results
  • Docker environment for reproducibility

Built with Biomni: This research is built upon Biomni, an open-source AI agent framework developed at Stanford University for biological and biomedical research.

Huang, K., Zhang, S., Wang, H., et al. (2025). Biomni: A General-Purpose Biomedical AI Agent. bioRxiv. https://doi.org/10.1101/2025.05.30.656746


Methodology

We tested three different approaches for literature curation and validated their performance by comparing Precision scores:

  • Default Biomni: A Biomni AI agent with default configuration
  • Custom Biomni: A Biomni AI agent with custom enhancements
  • PubTator: NCBI's annotation system

Performance Metrics

Currently validated using Precision only. Other metrics such as Accuracy and F1-score are not yet evaluated.

For detailed research documentation, please refer to:

  • BACKGROUND - Research context and motivation
  • METHODS - Detailed methodology and operational definitions
  • RESULTS - Performance comparison and metrics
  • DISCUSSION - Analysis of false positives/negatives
  • LIMITATIONS - Study constraints and future work

Conference Presentation

Presented at: The 48th Annual Meeting of the Molecular Biology Society of Japan

Date: December 3, 2025

Presention Material

Conference Poster

Download PDF


Reproducibility

All data and scripts needed to reproduce this research are available in this GitHub repository.

Repository: github.com/science-aid/agent-based-literature-curation

Feel free to reference and use these materials for your own research.


Contact

Takayuki Suzuki 📧 takayuki.suzuki@science-aid.com 𝕏 @sci_aid_tszk